Coyote hunting with a .308???

I would go for the 243 thats what I use for the yotes its the perfect round I think.

.220 swift, .22-250 rem, .243 win, pick 1

You really did not describe the distance you would like to shoot. And you did not specify if pelt damage is a concern?? Or not?? And do you reload??

For an Encore it would be pretty difficult to beat the 223 Remington cartridge for shots out to 300 yards. Bullet selection is fantastic, so you can go for killing power, or low pelt damage. And factory ammo is probably the best priced of any of the factory cartridges.

Personally before I would pay the price for a Pro Hunter barrel I would look at an MGM barrel, or even a BullBerry or Eabco. Normally they have 223 barrels in stock. And you can get a custom barrel for very little more money. And they do shoot. Tom.

I started Yote hunting 3 years ago. I went out and bought me a Kimber 84M Longmaster VT (.22-250) topped with a Zeiss Conquest 4.5x14X44mm. The rifle was a beauty and very accurate. However, I quickly got tired of carrying around a 10lb rifle and more importantly, I wanted something I could confidently shoot a deer (200+ yards) with when yote hunting in the fall. I sold my beautiful Kimber and bought a 6lb Remington 700 Mountain Rifle in .243 and kept the Zeiss scope for it. Wow - this is a great set-up. I can shoot .55gr ballistic tips at over 4,000 fps or 100gr at larger game. I can carry it all day and never get tired.

I'd recommend the .243, which can do everything the .22-250 can and more.