I've shot yotes with 00, and I'm sure by the damage that it did to them, that it'd be more than enough for deer, however, check out your state regs, here in KS, you can't use anything but slugs. If you use 00 shot, then a full choke or a tight mod/imp is necessary, if slugs, then use a fairly loose mod/imp or looser, so as not to deform the slug upon exit, or kick your arm off.