In my browning stalker my best deer load is IMR 4831 and a 135 gr sierra,shot 3 deer year before last and all 3 dropped where they stood,2 at 150 yds,2 were standing together,first one dropped the second fell on top of the first one so you could say I stacked them,
One was 250 yds dropped where it stood.
Best load for the 130 tsx was 66.5 grs of IMR 4831,shot a 185 lb boar @ 150 tds in the throat.
Tried 63 grs of R-22 a couple weeks ago with the 140 accura bond and it looked very promising.
Several powders worked really well in my browning.H414 worked well in both my win classic and brownig with the 130 sst's and R-19 and H4350 worked well with the 110 v-max if you want a good varmit load.

Herman - isn't the 135 Gr. Sierra a matchking type target bullet?

Yes it is match king,The biggest thing we have here is deer so it works fine on them. Haven't got my notes handie right now but I think I have it going around 3000fps with the 62 grs,max is around 67 grs.
Used a tsx on a hog last year and it worked fine also.Have used the sst on several deer and they work great too.
The sierra game king BTHP140 shot the same poi as the 135 gr.shot one @250 yds with it the deer dropped at the shot,when I went to get it,it was gone only a big blood puddle,found one drop of blood about 4 ft from where it dropped nothing more, five of us looked for it for 2 hours,hate it but lost the deer.Don't think the bullet opened up,found out later they are more for larger game.
Let my younger brother shoot one at 200 yds with the BTHP 140,I watched through field glasses,seen the bullet strike behind the front shoulder the deer took off didn't find one drop of blood or the deer ,so won't be using the game king BTHP any more but the game king SP should work fine.
The game king BTHP may work fine at a higher fps but there are too many other good bullets to use on deer here without the risk of looseing another one.

I just won't use the Gameking for hunting. A gunsmith friend who hunts a lot showed me a bunch of empty jackets from Gamekink bullets that had seperated completely from the core. I do however like the Sierra Pro-Hunter and have never had a problem with them in any caliber. I just put the scope on my new Savage 270 WSM Varmit rifle and its going to the range this afternoon. I hope to use RE-22 for mine. I do have half a case Of AA-MRP. It loads the same as AA-3100. My Nosler manual shows 3100 as the most accurate powder tested with the 140 grain Ballistic tip which I am going to try first. Of course that was in their test rifle.

James I haven't tried any of the mrp,but did try the AA3100 and the best I remember it shot very good with the 140 sst,couldn't find my target notes but did find what I got in fps.This is with a browning 23 in barrel. 65.5 grs gave me 3186 fps with a 6 shot group.This may give you something to compare the mrp too.