Has anybody tried these? I ordered a box for my .450 Marlin. It is supposed to shoot about 2 inches low at 200 yards when sighted in a inch high at 100 yards shooting a 325 grain bullet. It sounds like it will be a really good combination.

From the chart on their webpage, it looks like your .450 would be -4.2" at 200 if you sight in 1" high at 100.

Ok, I couldn't remember exactly the drop but that is not bad for that gun. The only problem with it is the recoil. It kicks worse than my buddies .375 H&H in a Ruger No. 1.