I haven't hunted many big game animals, but I would say that a cougar or wolf would be about the toughest especially if we are talking about with a bow(this is the bowhunting forum). Those might be classified as predators, but then how's about a grizzly bear? I believe that qualifies as a big game animal. What about a black panther. I bet the few of those that run around the Florida everglades would be tough to get with a bow!

TBO

Grizzlies and brown bears aren't that difficult to find and not that difficult to get in range. They could, however, eat you. I suppose that would qualify as tough....LOL

whitetails are a piece of cake compared to a BLACKTAIL..
Sheep are hard.
Goats are hard
Big Mulies are hard.
lions are the hardest i believe. no dogs.

Whitetail deer are really smart when it comes to hunting season.

I havent hunted anything other thna deer, but I believe a whitetail in an area with heavy hunting pressure is a completely different animal than a whitetail in an area with a low hunter density.

i would say the ruff grouse...thats a challenege in thick rough terrain

Mature Whitetail Bucks!

Without a doubt it's the Split Tailed Lounge Doe. No other critter requires the level of expenditure of resources, time, and effort for so little return.

mature longbeard on the ground without a blind...i've done it once with my recurve...took me 4 trys on a 5 year old bird...you gotta have your s**t straight for it all to come together!

Bigfoot been hunting him for 10 years!