what one is bigger and better for coyotes?

Same size bullet, the 22-250 is faster, the .223 is cheaper to shoot. Both will do wonders on a coyote.

22-250 vs .223

basically between those two calibers, its pretty much going to boil down to preference.

I have to agree both are good. I'm betting he's looking for a way to get the best of both worlds though. ive debated this amongst myself in the past wishing I could have 22-250 performance with the cost of .223 theres two routes you can go 1. start hand loading and 2. if you only intend to use factory loads, get a loose twist .223 chambered rifle Remington and howa and a few others make loose .223's with a 1 in 12 twist and use 40 to 45 grain ammo. this way you will get near 22-250 velocity and trajectory from a .223 and don't have to worry about over spin on the projectile which with light varmint projectiles can rip them apart in flight from excessive centrifugal force caused by tighter twist rates.

Bigger & better? 22=250, inasmuch as you get a little more range, and less wind drift for awhile as it is more hyper. Bigger kaboom too. I have used either a 223 or 222 Rem as I don't need to shoot over 200, and it is quieter in our settled areas. If I lived in the Nebraska flats or Montana, it would be the 22 250 for me.

I fur hunt so the .223 is my choice out of those 2 for sure!!!!!!!!,And my .223 is not a regular .223. Its a .223 ackley improved,dont get me wrong the 22-250 is an awesome gun and has a lot of speed, but it leaves to big of a hole on yotes, foxes, etc. Otherwise there both great guns!!!!!

Just get the .243 that you have been talking about, and outshoot both of those guns.

you guys getting big holes with the 250, have you tried ballistic tips??

just asking...i hit groundhogs between the eyes this summer with 55gr ballistic tips and a couple times i got an entrance atleast the size of a quarter...and only slivers looked to have exited...seemed it blew up on impact...which, i could care less what they do to groundhogs as long as they die...actually like explosive bullets just for piece of mind i k now it shouldnt go far if it hit the target or backstop...

seems if you shot a 40 or 45gr NBT from the 250, exits might not occur...i dont know though...havent shot a yote yet...i know a fox will be a mess...i wont bother...but think the yotes might be OK

I was debating the .223 and 22-250 for about a week. Thanks for all of the input on this site, it really helped me out.

I went to Cabela's today and purchased a Remington Model 700 SPS .223. It was in my price range and I have been really happy with the Rem Model 700's. I have not shot the gun yet because it was 15 degrees and snowing today with about a 20 mph wind. Gotta love Nebraska!