The thing is - someone who is in the 150+ yard class of muzzle loader shooting would of necessity be an experienced muzzle loader shooter, and would not likely be asking questions on a forum about bullet drop at 300 yards. The very question begs a realistic reply like Cayugad's.

Not disagreeing, my first reply was a more veiled insinuation at the same thing. Guess I'm just a bit sensitive to broadly generalized statements about longer range shooting.

First Off the world of modern muzzloading has NOTHING to do with old flintlock shooting and the ideas that surrounded them and their capabilities!!!! NOTHING.. a modern well made inline, modern low flash primers, 777 pellets and especially the new scopes, like the Nikon's BDC's and Leupold's Ultimate Slams make 150, 200 and 250 yards no big deal... once I sighted in my new Triumph Bone collector I had no difficulty hitting a pie sized metal plate at those distance by using the DOTS system on the first day of shooting it.. The bullet worked extremely well, my son who shot the rifle one time shot a big ole' doe last week at 150 yards with no problem whatsoever.. So I'd say modern muzzloading is more than capable with very little problem of shooting to 250yards without much effort...thanks to modern advancements.. especially in scope technology..amazing stuff on the market....

What was the wind and now many inches/MOA of hold compensation for it? 150 is one thing, but 250 and 300 yards are worlds apart in real-world conditions unless it's dead calm. IMHO scope technology does not make up for deficiencies in shooting form and solid field shooting position, and de-emphasize the importance of understanding exactly how your bullet is moving as it travels downrange.

A typical "flat" shooting ML load will be pushed greater than 15 inches by only a 5mph wind at 300 yards. It was only 3-4 inches at 150 yards so that's a BIG difference. If you judge the wind off by 2.5 mph your bullet is 7.5 inches off to the right or left, turning it into a gut shot in one direction or a potentially miss/wounding shot in the other. I carry a wind meter in the field but have ended up passing on any shot over 250 yds with more than a whisper of a breeze.

The average shooter would have a hard time keeping 3 shots inside 4 inches at 250 yards in the hunting field with a bolt action .270 and 3x9 power scope...Much less with a muzzleloader...

Ballistic tables are references and should not be substituted for load development and experience...You simple can't take a 50 yard target, look at a table and then expect to hit the vitals of a deer out to 250 yards...Too many variables...