Right behind the shoulder is the best way to go. This shot is very lethal and allows the most margin of error in the shot, than any other shots. If they go down in 20 yards instead of dropping in their tracks, then I could care less. Both are dead deer, but one shot was much safer than the other. So common sense says, "why bother shooting anywhere else?".

I can consistently shoot 500 yard, fist sized groups at the range, with my deer rifle, but still am not going to take anything less than the "best shot", at a deer.