RE: .223 or .22-250 for yotes??
IMO the 223 is my choice.Ammo is cheap and it is good well past 300 yds.
I shoot Wolf FMJ stuff out of my AR-15 ,it shoots good but I don't know how their HP ammo expands. Where I live there is too many houses to be shooting fmj at yotes.
If you go with a 233 ,I would try Federal American Eagle AE223G .It shoots great and it's cheap.