Yes, your Wolverine will fowl a scope. You can protect the scope with a scope cover or by putting electrical tape around the scope. The electrical tape is easy to wipe off. All muzzleloaders for the most part will fowl scopes and other things with their blow back from the breech.

As for what projectile a .45 caliber will shoot.. I am sorry I can not help you there. All I can tell you is my Wolverine likes around 85 grains of FFFg powder and medium to heavy weight bullet sabot combination... Try any of the Knight Sabot bullet combinations.. they tend to shoot real well from Knight rifles as do Barnes Expanders. All of them will kill a whitetail and some surprising ranges also, if you can place your shot...

Good luck with your rifle..