RE: Which caliber is responsible for the most wounded deer?
Personal observation, .243. I have seen more deer shot and lost with a .243 than any other caliber. Stats, 10-15 deer lost over 5 years. It was a buddy of mine's favorite rifle.
For what it's worth, I have shot many deer, and have seen many shot with a .30/30 and not a single one of them was lost. These stats are based on a total of 30-40 deer over a 10 year period. None were attempted at over 100 yds. Just not that many really long shots where I hunted then.