Let's put it this way. A century ago, (Actually, a little longer than that) hunters used black powder, cartridge rifles to kill buffalo at longer ranges than that. These were things like 45-70's, 45-90's 50-110's etc. Although menacing to look at, and totaly useable, even today, they just don't compare energy wise to todays high velocity rounds. Sectionaly, the big slugs are effective, but modern spire point, high energy bullets out of your 30-06 are more than adiquite to kill your moose at 300 yards and beyond. But it is up to the shooter to be responsible enough to limit the shot to more practical ranges. 2-300 yards is my maximum, due to any number of effects downrange. Good luck.