That is harder to do than in areas where they are running around in every thicket, but the fact remains that the bucks still have to be there. Generally I feel your average joe hunter isn't that skilled at finding or pursuing mature bucks in heavy hunted areas. Just like catching fish from a "fished out" stream.
The above described hunter has to work harder in his pursuit of a mature deer, just because there may only be one, that will ever come thru his huntable land in a given season, and he has to be in the right spot, when one of those opportunities occur.