I think that the .500 S&W was designed by a group of engineers that wanted to prove to the world that their johnsons are bigger than Dick Casull's. This is a classic case of penis envy manifesting itself in the form of firearms cartridge design.
Wow.....now that's hitting the nail on the head!!!!!
The overwhelming number of owners of the .44 Magnum are not capable of shooting them well to say nothing of cartridges with more recoil. The .500 S&W is for a very very small number of handgunners that can shoot them and manage the recoil.
The .480 Ruger is worthy of consideration and it also is a handful.....but far more manageable than the .500.