Stone cold last year my hunting partner and I went in on a box he got excellent results while I ended up going back to the 240's. I got my best groups shooting 90 grains of Pyrodex with the 180's. My partner stuck with his 100 gr of pyrodex pellets. His load accounted for a mulie doe and she made it maybe 75 yards after an in n' out through the rear of the lungs, I felt the small hole might have accounted some for the distance she travelled(It looked to me like the bullet hardly expanded)! I shot a mulie doe and whitetail doe with the 240's both double lung, 1 dropped at the shot and the other muster a few steps then crumpled(my wound channels was what I have come to expect from the 240's).
Only way to know is T & E. You can always go back to what worked previously, that is what the offseason/range are for!
I am going to try the SST and deadcentre's this fall with T7. Last fall I couldn't get the 240 gr deadcentres to fly worth a hoot with pyrodex but since I have some still in my range box and having bought a keg of T7 might as well have more reason to head off an blow smoke. If all else fails I already have my go to load figured out
Best of luck!!