I use a 280 Remington with 175 gr. Nosler Partition handloads. This will cleanly anchor hogs that are big. I own 312 acrres of land and lease another 250. We have an abundance of feral hogs. I have taken as small as ten pounds to one weighing 486 on the butcher's scales. Never had a problem when using the mentioned handload. I have also taken several with a 257 Roberts and 117 gr. Hornady BT Interlock.