DJ,
I've had great results with both W296 and H110. I shoot Hornady 240gr XTPs over 24gr of either W296 or H110 and velocities out of my 9.5" Ruger SR are in the neighborhood of 1450fps. I also load 300gr XTPs (seated to the second crimp groove, this is a compressed load) over 21gr of W296 with velocities around 1300fps. Both loads are moderately heavy recoil but still within allowable pressures. I took 2 deer last season using this last load with impressive results. Hope this helps...