Mostly cons. The few exceptions would be fur bearing animals to deture pelt Damage. The other would be the use of certain designed cast bullets which open large wound chanels as well as deep penatration. Such a bullet would be bullets cast by the LBT moulds with the long flat nose. They have been used with great success by Ross Seyfried. In middle calibers to take all different species. There is a very good atrical by Ross in rifle magazine explaining the LBT bullet moulds and some elk taken with a 366 caliber bullet of just 160 grains. Complete through shot on an elk with huge blood trail and good internal damage. These moulds were off the market for some time but are now back in production. The LBT bullets may not be the only bullet to use the long Flat nose design. Anyway cast bullets are a whole other subject and don't reall fall in the soft point or the traditional solids. I have only been into the cast bullets for a short while. As far as the expense of buying a bigger rifle goes, if one needs a bigger rifle for a given application they should probably get one rather than trying to make do with something smaller. In many models the 458 and 375 don't cost much more than the standard calibers. My 416 Ruger was the same price as all the other calibers.
For all my NA hunting I am very comfortable with the 30-06 and the 45-70. The Speer manual recomends the 350 grain RN at about 1900 FPS for the geart Bears and big moose. The 30-06 has worked fine for all the other species. The new bullets such as the Barnes X bullet and Nosler accubond and Swift A-Frame has given a new lease on life to many of the middle calibers such as the 279, 280 and 30-06. Ihave yet to try out my 270 WSM but I think it will fit right into this mix.