Comercial autoloaders are designed to shoot anything that you can buy of the shelf. AS long as you don't go beyond maximum pressures you aren't going to hurt anything. The only common autoloader that I know of that you really have to limit your loads and powders on is the M1 garand, its oprod is its achille's heel, it will bend or break if the pressure curves aren't correct. This is mainly because the gas plug is not adjustable, but even the garand can be updated with an adjustable plug to be able to shoot commercial loads. Most american autoloaders are self adjusting especially hunting rifles because lets face it most hunters aren't necessarily too gun savvy, some european autoloaders have a manual gas adjustment system where you adjust the amount of gas bled off so that there's just enough left to consistantly cycle the action.