I can pretty much reload all of my and my wife's smokeless powder guns with IMR 4350 and IMR 4064 ('06, 7-08, 7-mag, .243), and if I really put my mind to it, I could probably work on some new loads and narrow it down to one powder for all except my .22 hornet, which I use IMR 4227 for. I'm a big fan of the IMR powders! Been using them for over 30 years with much success and zero failures!