The 280 is the first cartridge that I ever reloaded for. I have had the most uniform results using IMR4831. This is in bullet weights ranging from 120-160 gr. Lately I have been using a max load of RL19 behind a 140 gr. NBT as my deer buster with a Federal 210 primer. Over my chrony I get a velocity a few fps above what is listed in the Nosler reloading guide. If you don't really need to reload the Federal Premium load you mentioned is probably the best all around load for the 280. This combination is enough for elk as long as you take broadside shots and limit your range to 300 yards or less.