I shot a couple of coyotes a handful of years ago with a Walther PPK/S just to claim the experience. My wife shot a doe several years ago with her 2.25” SP101. In college, I used my G19 to fill a couple of doe tags.
It’s handgun hunting - there’s no trick to it, a hunter simply needs to understand the limitations of their cartridge and of their own ability to deliver bullets on target at range, in the conditions of the field.