Hunt for the most expensive animal you think you will ever want. They won't get any cheaper and you may not get another chance. For instance I did a Stone Ram early in my hunting career and it only ran me around $5K. That's a $30K hunt now. I once passed on the chance to do a White Rhino in RSA with a broken front horn for $6K. That's a $100K hunt now. I also let a big sable go because I didn't want to pay the additional $1500 trophy fee when I was already in Africa. Price a sable hunt now.
Words of wisdom from someone who has been there and done that.