I used them on a number of deer they are very accurate I use 120 grains of Blackhorn 209 and the 250 grain SW they work quite well to 90 yards I have not shot any deer be on that distance as it is thick cover where I hunt around here. There are reports of people having trouble getting them to open with light loads.
I do not use them any more as I switched to Bloodline 250 grain bullets because they are the best terminally.