I don' t shoot 45 cal, but powerbelts do well in my 50 cal.

I recently shifted from 245 grain w/ 100 grains of 777 to 295 grain with 90 grains of pyrodex (I ran out of 777 in the middle of a hunt) and it got more accurate! Easy 2 inch groups at 100 yards. I would not try this load at 200 yards though, it just looses too much energy.

Chubber