I see 55 gr. Hornaday V-max recommended a lot for the 22-250. I'm beginning to hand load and have a classic lee loader for that caliber, and Lee gives a starting load of H4895 using the supplied dipper. (unfortunately, i don't recall the exact grains)

Is that 55 gr. a good place to start? Lee also lists several other starting loads with various lighter bullets (40-55 grs.), and I could start with one of those. For the moment, I'm going to stick with that powder till I get the basics down.

The gun is a Savage Axis with a barrel twist listed as 1 in 12. I have gotten solid groups with Winchester 45 gr. jacketed hollow points in factory ammo previously.

I'm in eastern Kansas and would predict it would get most use on coyotes and woodchucks, maybe the occasional fox or bobcat.