I have done a lot of shooting with the 50 gr Pyrodex pellets in my TC. muzzle loaders. I can see no need to ever load more than two of those pellets. I have taken and seen taken many deer with two pellets and several combinations of bullets. They go down like a rock. I fire three pellets ONCE behind a 300 gr Hornady XTP. That was more than enough of that expierence.