I have a freezer full of Elk. 7mm-08 Nosler Partition. Less than 50 yard shot. The bullet fragmented like it's supposed too. and the Elk ran maybe 30 yards.
The exit wound was rather small, because the partition fragments as designed. So only the core exits. If I had to follow a blood trail, I'd say it wouldn't happen.
However, 7mm-08, I practice for hours before the season. I'm not flitching because the recoil is nil. & I love the rifle. And I'll be using it for Elk & Bear this year.
When deer season comes along, I'll downsize to my .243