So am I Grouse. I never shoot for the shoulder and rarely in the neck. I'm talking behind the shoulder taking out both lungs. The hydrostatic shock from the .243 (100 gr bullet) and the 270 (130 gr) causes dramatic tissue damage. I hit a buck coming straight on with the 270 once and drove him straight back on his butt and he never got up.
I guess you can say I've been extremely lucky. My friend, who swears by his 30-06 and shoulder shots, almost always has his deer run off, even if only for a short distance. I make fun of him too because we hunt a lot in the strip mines and his deer usually find their way to the bottom of one nearby.