Save the shoulder and go with 25-06 but keep a good eye on yardage.Just because the trajectory is flatter doesn' t mean it will kill the target.As far as accuracy,the rifle can only be as accurate as the shooter so Practice practice practice the fundamentals that are essential in shooting a rifle.A.300 Rem Mag will drop a deer out to 1000 yards if you could put the shot in the precise target area but I can' t see a 25-06 doing that.I would have to say 500 yards at most with the25-06 but then agin you would still have to show the proper fundamentals for a shot like that.300 yards is the farthest I would shoot at any deer anywhere in any conditions.Not to say that I have but that would be a good deadline on max yardage for hunting deer.