Slugs have evoled over the last 30 years I've been hunting. When rifled barrels came out I used 12 gauge Winchester Platinum Tip 400 grain slugs. I killed many deer with that set up. They all died quickly with huge blood trails.

I've also used Remington Copper Solid 20 gauge slugs to take an 8 pointer at 100 yards. He only ran 25 yards before expiring.

Hornady's 20 gauge sabot slug is basically the same bullet; (weight, BC, and sectional density are identical although the jacket thickness is greater in the 450) as my black powder rifle and my .450 bushmaster.