Super - in my back up '06 I plan on using Barnes TSX 180 gr bullets over 49 gr of IMR4064. That's what my friend used when we went to Newfoundland. His dropped right where it stood with a high shoulder shot. Mine was shot with 180 gr Sierra Game Kings. I hit him square in chest on a frontal shot then 2 more through the lungs when he turned sideways and put him down. A couple guys heard me shoot the 3 shots and thought it was a semiauto. That's how fast I worked the bolt on my Tikka.
BTW - that bull was standing on a dirt 2 track as we rounded a turn and saw him about 150 yards out. My guide/outfitter told me shoot him now before he takes off. This guy's been hunting moose for close to 50 years so I took him at his word.
But we're getting away from traditional muzzleloading here. I''m sure my .58 will put a ginormous hole in a bull's lungs and he won't go far.