Every time I've hunted hogs has been over dogs so the hogs were wound up with fight or flight occurring. Weight on the hogs either I or hunting buddies shot on these hunts ranged from 150 to 275 with results of DRT to running off for a 100 yards or so. Almost all of the shots taken were body shots as we were trophy hunting. As best I can recall, calibers were from 270 through 350 Marlin.

For the OP, the advice of shooting a .223 or 7.62x39 in the ear (brain shot) seems like good advice. If you're hunting for meat, you wouldn't be worried about messing up a trophy with a head shot. If you go to our airgun forum, one member has posted a head shot (between the eyes) hog with a .25 airgun that was DRT. The pig looked more like a javelina size than a large hog but it's pretty hard to argue with the results. Good luck with your hunting and let us know the results.