Considering i shoot the Barnes bullets at smokeless ML speeds, im well aware of what they may do. It requires far more velocity that what is being discussed in this topic. 80gr of BH209 wont even come close to ripping apart a 45cal or 44cal 225gr XPB. Velocity would be in the 1700fps range with 80gr of BH209 and a 225gr bullet.
This one (on the left) was shot at just over 2300fps in my ULA model 20 50cal. It retained 205gr in a similar torture test. The one on the right is a 275gr XPB shot at roughly 2200fps.