I don't even know how many different calibers I've used on whitetails. I've taken them with rifles, pistols, bows, crossbows, black powder and shotguns firing both buckshot and slugs. But if I had to pick one as my overall favorite it would probably be my 7mm Mag simply for the fact that I've had it since I was 13 and have done most of my hunting with it. I've hunted in more than 10 states with it, 3 Canadian provinces and it has gone to Africa 5 times. It has always worked and will continue to do so for as long as I can pull the trigger.