I have not used Barnes bullets in calibers smaller than .308, but I have had excellent results in both accuracy and performance with TSX bullets in .375 caliber and both TSX and TTSX bullets in .30 caliber.

In 2005 I used 300 grain TSX bullets in my .375 RUM on a variety of African animals from Bushbuck to Buffalo. These bullets shot sub moa in my Rem 700. The only one that I recovered was from the Buffalo which was a one shot kill, the bullet passed through the near shoulder, the lungs, and was found in the off shoulder. That bullet had expanded to the classic Barnes mushroom and still weighed 300 grains.

In 2007 I made another hunt in South Africa with my .375 RUM, this time shooting 270 grain TSX bullets. These bullets also shot sub moa in my rifle, and they made one shot kills on a variety of Plains Game animals from Steenboks to Eland, including a gemsbok shot at a lasered 348 yards. Most of the bullets completely passed through the animals, but the two that we recovered again were the classic Barnes mushroom.

In 2010 I built a .300 Weatherby, and the first hunt that I used it on was for exotics in West Texas where I used 168 grain TSX bullets to make one shot DRT kills on three animals from a Blackbuck to an Aoudad. Both 168 and 180 grain TSX bullets shoot sub moa in my rifle.

In the fall of 2010 I also shot a 5 point Montana bull elk with my .300 Weatherby and a 168 grain TSX bullet. The bullet passed through the bull, just behind his shoulders, and he fell dead within 10 yards of where he was shot. There was blood sprayed on the snow 10 feet out from each side of the bull.

In 2012 I used my .300 Weatherby on another South African hunt, this time shooting 168 grain TTSX bullets. These bullets also shoot sub moa in my rifle, and again they made one shot kills on 5 Plains Game animals including a baboon at 290 yards and a Klipspringer at 310 yards. The bullets completely passed through 3 of the animals, but the other 2 bullets were recovered , and again they were the classic Barnes mushroom, identical to the mushroomed TSX bullets that I had recovered from other hunts.

In the fall of 2013 I killed another 5 point Montana bull elk with my .300 Weatherby and a 168 grain TTSX bullet. The bull dropped dead as the bullet entered his near shoulder and stopped just under the skin of his off rear leg. It had also expanded to the classic Barnes mushroom.

Last year I took my .300 Weatherby to New Zealand where it made one shot kills with 168 grain TTSX bullets on 5 animals there. These included a great Red Deer stag and a Fallow deer shot at a lasered 320 yards. All of those bullets completely passed through those animals, and all animals fell dead within 10 yards of where they were shot.

I haven't tried Barnes bullets in any of my other rifles that I use primarily for North American animals like deer and pronghorn antelope as I have had almost 40 years of success with common cup and core bullets like Sierra GameKings and Nobler Ballistic Tips.