I think you're making this more difficult than it needs to be. A lot of bullets will deliver very fast kills, and a lot of bullets will stick together while punching through bone. I personally would rather deliver a fast kill with a lighter built bullet to the vitals than worry about crippling deer by breaking their shoulders. Conversely, I'd honestly expect SLOWER kill from a harder bullet, they don't open as much and don't transfer as much energy/momentum to the game. To knock deer off of their feet "DRT," you need to dump a lot of energy very quickly - hard bullets won't do that. Deer just aren't that tough, so they don't offer enough resistance to expand harder pills and scrub off momentum - it just puts a deeper hole in the ground on the back side.

100fps and 200ft.lbs. difference will not matter in the least. Either will kill deer fast when placed right, as will a more frangible bullet like a Winchester 150grn BST. You've been posting a lot about this lately, and honestly, I feel like you're chasing your tail. You simply need to find an accurate load, not worry so much about maximizing your weight retention.