The gentlemen that developed the Savage smokeless live about 30 minutes up the road from me here in NC...The elder is gone but the son still posts regularly on the NC hunting website...He says they developed the Savage around the .300 XTP Hornady in that .45 caliber...They go down east each year and he has killed some deer at ridiculous ranges...It seems to work well for him...
I shoot the .429 simply because the ballistic coefficient is better than the .45...It works as well...