Neither would I, based on my experience hunting bears. Put a well made bullet from any of those cartridges into a bear's lungs and you can get the skinning knife ready. I've personally seen a treed cattle killing bear laid low with a single round through the brain from a .22 pistol. Now I'm not saying a .22 is a good bear round but it was the only gun on hand and it sure killed that one graveyard dead, which proves bullet placement is more important than bullet size.