I'm not sure. The 460s are considerably longer than the casulls. I have not started loading for either yet. I have gone out a couple of times and ran about 50 rounds of 454s through her and about 50 rounds of 460s each time. I absolutely love this gun. It puts my 44 mags to shame. When I get time I will start reloading. That is when I get a chance to get some bullets. I've got brass, primers, and powder, just nothing to top it off with yet. I will look into using the Casull dies for it, if not Ill order some 460 dies. I think I will primarily shoot 460s. Casulls are Ok, but with the ability to shoot 460s I see no need for the smaller Casulls. And for 45s, ive got plenty of guns that shoot long colts.