Not what I asked. I'm not comparing clean to fouled. I'm asking about comparing clean to clean. As in taking a shot on a clean barrel, and clean the barrel, and take another shot. Complete cleaning between every shot.

They're are some guns that will be accurate doing that. Those guns don't need to be hunted on a fouled barrel if you sight them in for the clean barrel.

Now, if you try that test, and your groups are all over the place. Then that gun should be sighted in with a fouled barrel, and hunted that way.