Having hunted Elk for several decades in Colorado and mostly Wyoming and carried many different rifles ranging from .257 Roberts to .300Wby Mag. I can say with a reasonable amout of certainty that what ever YOU shoot well will be effective. Put the leak in the right spot and it will die.
I used to arrogantly tell my wife not to shoot at any Elk with her .308 beyond 200 yards unless I was there to back her up with my Belted magnum. This year, in Wyoming, she shot her Elk at 545yds, uphill, in a 30mph+ crosswind. My Elk was right next to hers. Hers went down on impact and mine took two more shots. What can I say, she shoots better than I do.
My opinion: SHOT PLACEMENT is paramount and projectile selection is right up there in importance.
P.S. - Now that I had the misfortune of moving to Texas (annogram for Taxes), I'll likely buy a .308 for myself. Great round!!!