I've killed a pile of deer with home-cast 435 gr 54 cal maxiballs shot over 100 gr loose pyrodex. This was my Renegade's preferred load. I always lubed with bore butter. Just squoze some out and filled the grooves, nothing tricky about it.
There may be "better" conicals out there, but I shot them from a gun with a peep sight. Within open-sight ranges, I never found these bullets lacking anything.