I almost always aim for the vitals. I never take a shot that is iffy. But I have taken a few neck shots- every time the deer dropped like it had been struck by Thor's hammer. Each time, I had confidence that I could make the shot, and there was no other shot available. One time it was on a wounded deer that needed to be put down. Not trying to boast or anything, but if the deer is not moving, is inside of 80 yards, and I have a steady hold, I can drop a deer with a neck shot as consistently as most other hunters with a vitals shot at the same range.