Let me see...Daniel Boone died in his sleep at 85, he never used anything but a roundball and was a market hunter in his younger days...
I started using a flintlock back in 1977, it was a .45...I never lost a deer because I was using a roundball...I've since rebarreled the .45 to a .40 and made a .54 back in the 70s, mainly because we have black bears on our farms...
Ain't nothing wrong with a roundball, it will kill as far as you need to be shooting with open sights...