handloader,

Of the powders you mention, I use H-4350. Since Hodgdon reduced the grain size it meters very nicely. The primary reason I like Hodgdon extruded powders is the extreme technology. The powder is very consistant from one lot to another and is insensitive to temperature changes. I get the same velocities at 100 degrees as I do at 13 degrees. The result of this is I also keep the same zero of my rifle. I wish I could figure out how to post a picture, I' d attach a copy of a ' 06 five shot group. With the 165 grain Sierra HPBT, CCI BR2 primers, Winchester cases and 59.5 grains of H=4350 the group measured .247" c/c. Velocity is 2830 fps.The extreme velocity spread of 10 shots was 11.0 fps. Standard deviation was only 5.1 fps. These results are excellent. Right now I' m playing with the Hornady Interbond bullet. The velocity spread is very close to identical. Good luck.