I love using my .410 for squirrels.If you ask me it' s the best gun to use.
With a 12 or 20ga you just shoot them all up and a I' m just not accurate enough with a .22.I had a bad experience with my .22 once and swore I would never use it again.I shot a squirrel 4-5 times before it got away and the last time I saw it it had blood all over it' s stomach.Made me sick.EVERYTHING should be killed quickly and not suffer at all.