Ron, is it a compound? Single cam or two cam? Steel Cables with teardrops? or does the string attach to the cam? Help us out here.

I take it from the title of your post, that you are wondering about twisting the string. The answer is YES. Twist it, but don' t overdo it. Twisting it too much, can shorten your draw length (usually about an inch) and reduce your draw weight.

Without more info about your setup, it will be difficult to answer your questions.