I generally agree with RR. I'm not sure when everyone started thinking that a pass-through was best, but my experience has been the opposite. Maybe some guys are forgetting that they put the bow up for the season and picked up their rifles? While you want an animal to bleed out quickly when hit with a broadhead, a bullet that completely expends its stored energy inside an animal almost always has greater effect than one which passes through and expends what's left of it somewhere in the dirt on the other side.
Most of my shots are under 200 yards. Given than, I generally see the best performance on deer and pronghorn with a bullet of 100-150 grains (regardless of caliber), driven somewhere between 2600 and 2800 fps at the muzzle. I know a lot of guys swear by partitions and more "premium" bullets, as well as "magnums", but I haven't experienced the need. For elk and caribou, I've used from 140-190 grain bullets, driven at about the same velocities as I load deer rounds at.