.243 is an excellent rnd for mulies at maybe 300yds or closer, but bullet drop at longer yardages make it a guessing game on where to aim, and some times mulies don't give ya a long time to sit around and figger it out........folks need to realize huntin mulies in the sage brush ain't like shooting a whitetail out of a foodplot or from around a feeder no offense ment just my two cents